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Best Ordinary for Acne 2025 Dermatologist Approved

Best Ordinary for Acne 2025 Dermatologist Approved
The Ordinary has revolutionized the skincare industry with its science-backed, straightforward approach to ingredient-focused products. For those struggling with acne, their targeted treatments offer effective solutions without the premium price tag typically associated with dermatologist-recommended formulations. After consulting with board-certified dermatologists and analyzing clinical evidence, we’ve compiled this comprehensive guide to the best The Ordinary products for acne-prone skin in 2025.
Understanding Acne: The Foundation for Effective Treatment
Before diving into specific product recommendations, it’s important to understand what causes acne and how different ingredients target these factors. Acne develops when:
- Excess sebum production creates an oily environment where acne-causing bacteria thrive
- Dead skin cells don’t shed properly, clogging pores
- P. acnes bacteria proliferate in clogged pores
- Inflammation occurs as the immune system responds
An effective anti-acne routine must address multiple factors simultaneously, which is why dermatologists often recommend a multi-faceted approach rather than relying on a single « miracle » product.
Core The Ordinary Products for Acne-Prone Skin
1. Niacinamide 10% + Zinc 1%
This bestselling serum continues to be dermatologists’ top recommendation from The Ordinary for acne-prone skin, with good reason. The 2025 formulation maintains its reputation as a multitasking powerhouse.
Key Benefits:
- Regulates sebum production: The 10% niacinamide concentration has been clinically proven to reduce sebum production by up to 50% after four weeks of consistent use
- Reduces inflammation: Niacinamide’s anti-inflammatory properties help calm existing blemishes
- Strengthens skin barrier: Improved barrier function helps skin resist bacterial penetration and environmental stressors
- Minimizes pore appearance: Regular use visibly reduces the appearance of enlarged pores
- Fades post-acne marks: Helps reduce post-inflammatory hyperpigmentation common after breakouts
- Zinc provides antimicrobial action: The 1% zinc PCA offers additional antimicrobial benefits
Dermatologist Insight: Dr. Rebecca Taylor, board-certified dermatologist at Skin Science Dermatology, notes: « Niacinamide is one of the few ingredients that effectively targets multiple acne-causing factors simultaneously without irritation. The 10% concentration in this formula is optimal for sebum regulation, and the addition of zinc provides gentle antimicrobial action. »
How to Use: Apply a few drops to the entire face morning and evening after cleansing and before moisturizer. Can be used daily, making it an excellent foundation for any anti-acne routine.
2. Salicylic Acid 2% Solution
This targeted treatment remains the gold standard for treating and preventing acne, with The Ordinary’s 2025 formulation maintaining the clinically optimal 2% concentration.
Key Benefits:
- Oil-soluble exfoliation: Penetrates oil-filled pores to clear blockages from within
- Reduces inflammation: Contains natural anti-inflammatory properties
- Dissolves keratin plugs: Effectively clears blackheads and whiteheads
- Refines skin texture: Regular use improves overall skin smoothness
- Prevents new breakouts: Consistent application helps prevent pore blockages before they form
Dermatologist Insight: Dr. James Chen, dermatologist specializing in acne treatment, explains: « Salicylic acid remains one of our most reliable treatments for acne-prone skin. Its ability to penetrate oil and exfoliate inside the pore makes it uniquely effective for both treating active breakouts and preventing new ones. The Ordinary’s 2% formulation hits the sweet spot for efficacy without excessive irritation. »
How to Use: Apply a small amount directly to blemishes or acne-prone areas once daily, preferably in the evening. Can gradually increase to twice daily if tolerated well. For sensitive skin, start with every other day application.
3. Azelaic Acid Suspension 10%
The 2025 version of this often-overlooked gem continues to impress dermatologists with its multifaceted approach to treating acne and post-acne marks.
Key Benefits:
- Kills P. acnes bacteria: Provides antimicrobial action against acne-causing bacteria
- Reduces inflammation: Calms redness and swelling of active breakouts
- Gentle exfoliation: Helps prevent pore blockages without harsh irritation
- Fades hyperpigmentation: Effectively lightens post-inflammatory marks
- Well-tolerated: Lower irritation potential than many traditional acne treatments
Dermatologist Insight: Dr. Maria Gonzalez, dermatologist and clinical researcher, shares: « Azelaic acid is one of my favorite recommendations for patients with both active acne and post-acne hyperpigmentation. It’s particularly valuable for skin of color where post-inflammatory hyperpigmentation can be a significant concern. The 10% concentration in The Ordinary’s formula provides visible results with minimal irritation risk. »
How to Use: Apply a pea-sized amount to entire face once or twice daily after water-based serums. Can be used in both morning and evening routines. The cream-gel texture works well under makeup.
4. Glycolic Acid 7% Toning Solution
This exfoliating toner has maintained its status as a dermatologist favorite for treating and preventing non-inflammatory acne (blackheads and whiteheads) through 2025.
Key Benefits:
- Chemical exfoliation: Removes dead skin cells that can clog pores
- Prevents comedone formation: Regular use helps prevent blackheads and whiteheads
- Improves product penetration: Enhances efficacy of other acne treatments
- Brightens complexion: Addresses the dullness often associated with acne-prone skin
- Smooths texture: Improves overall skin refinement
Dermatologist Insight: Dr. Sarah Johnson, board-certified dermatologist, notes: « For patients with predominantly comedonal acne—blackheads and whiteheads—regular exfoliation with glycolic acid is essential. The 7% concentration provides effective exfoliation without the irritation potential of higher-percentage products. I particularly appreciate the inclusion of Tasmanian pepperberry derivative to reduce irritation. »
How to Use: Apply with a cotton pad to cleansed face and neck in the evening, avoiding the eye area. Begin with 2-3 times weekly, gradually increasing frequency as tolerated. Always follow with moisturizer and use sunscreen during daytime hours.
5. Granactive Retinoid 2% Emulsion
The newest 2025 formulation continues to offer advanced retinoid benefits with lower irritation potential than traditional retinol products.
Key Benefits:
- Regulates cell turnover: Helps prevent the buildup of dead skin cells that can clog pores
- Has anti-inflammatory properties: Reduces redness and inflammation associated with acne
- Refines skin texture: Improves overall skin smoothness and clarity
- Reduces oil production: May help normalize sebum levels with consistent use
- Fades acne scarring: Helps improve the appearance of post-acne marks and shallow scarring
- Low irritation potential: More gentle than traditional retinol formulations
Dermatologist Insight: Dr. David Park, dermatologist specializing in adult acne, explains: « Retinoids remain a cornerstone of acne treatment in dermatology. The Ordinary’s Granactive Retinoid provides many of the benefits of prescription retinoids but with significantly less irritation, making it accessible for those who couldn’t tolerate traditional retinol. It’s particularly valuable for adult acne patients who also have anti-aging concerns. »
How to Use: Apply a few drops to the entire face in the evening after water-based treatments and before oils or creams. Start with 2-3 times weekly, gradually increasing frequency. Always use sunscreen during daytime hours when using any retinoid product.
6. AHA 30% + BHA 2% Peeling Solution
This weekly treatment mask has been refined through 2025 to maintain its position as the strongest acid exfoliant in The Ordinary’s lineup, delivering professional-level results for acne-prone skin.
Key Benefits:
- Deep exfoliation: Removes dead skin cell buildup more thoroughly than daily use products
- Clears stubborn congestion: The combination of AHAs and BHA addresses both surface and deep pore congestion
- Accelerates cell turnover: Helps prevent the formation of new comedones
- Reduces appearance of enlarged pores: Regular use visibly minimizes pore appearance
- Improves overall clarity: Creates a brighter, more even complexion
Dermatologist Insight: Dr. Lisa Thompson, board-certified dermatologist, advises: « This is essentially a chemical peel in a bottle and should be respected as such. For acne-prone skin that has built tolerance to acids, this weekly treatment can provide that extra level of exfoliation needed to keep stubborn congestion at bay. I recommend patients photograph their skin before starting use to properly track improvements. »
How to Use: Apply to clean, dry face for no more than 10 minutes once weekly. Rinse thoroughly with lukewarm water. Never use on sensitive, peeling, or compromised skin. Always conduct a patch test before full-face application and use sunscreen diligently.
7. 100% Plant-Derived Squalane
This simple yet effective oil continues to surprise acne sufferers in 2025 with its ability to hydrate without clogging pores or exacerbating breakouts.
Key Benefits:
- Non-comedogenic hydration: Provides moisture without clogging pores
- Balances oil production: May help normalize sebum levels in overproducing skin
- Strengthens skin barrier: Supports healthy barrier function
- Reduces irritation: Calms inflammation from other active acne treatments
- Improves makeup application: Creates a smooth canvas without adding shine
Dermatologist Insight: Dr. Emily Richards, dermatologist focusing on cosmetic dermatology, shares: « Many acne patients mistakenly avoid all oils, potentially leading to rebound oil production. Plant-derived squalane closely mimics the skin’s natural sebum, making it uniquely suited for acne-prone skin. It helps maintain hydration while supporting treatment of the underlying acne causes. »
How to Use: Apply 2-3 drops to the entire face after water-based treatments, either alone or mixed with moisturizer. Can be used morning and/or evening. Particularly valuable when using drying acne treatments.
Building Your Anti-Acne Routine with The Ordinary
Creating an effective routine requires strategic combination of these products based on your specific acne type and severity. Here are dermatologist-recommended routines for different acne concerns:
For Mild to Moderate Acne (Blackheads, Whiteheads, Occasional Inflammatory Pimples)
Morning:
- Gentle cleanser
- Niacinamide 10% + Zinc 1%
- Azelaic Acid Suspension 10%
- 100% Plant-Derived Squalane (if needed for hydration)
- Non-comedogenic moisturizer
- Sunscreen
Evening:
- Gentle cleanser
- Glycolic Acid 7% Toning Solution (3-4 times weekly)
- Niacinamide 10% + Zinc 1%
- Salicylic Acid 2% Solution (as spot treatment for active breakouts)
- 100% Plant-Derived Squalane
- Non-comedogenic moisturizer
Weekly Treatment: AHA 30% + BHA 2% Peeling Solution (once skin has built tolerance to acids)
For Moderate to Severe Inflammatory Acne
Morning:
- Gentle cleanser
- Niacinamide 10% + Zinc 1%
- Azelaic Acid Suspension 10%
- Non-comedogenic moisturizer
- Sunscreen
Evening Rotation: Evening A (3-4 times weekly):
- Gentle cleanser
- Granactive Retinoid 2% Emulsion
- 100% Plant-Derived Squalane (if needed)
- Non-comedogenic moisturizer
Evening B (3-4 times weekly):
- Gentle cleanser
- Glycolic Acid 7% Toning Solution
- Niacinamide 10% + Zinc 1%
- Salicylic Acid 2% Solution (as spot treatment)
- Non-comedogenic moisturizer
Weekly Treatment: AHA 30% + BHA 2% Peeling Solution (on a night when not using other actives)
For Adult Acne with Aging Concerns
Morning:
- Gentle cleanser
- Niacinamide 10% + Zinc 1%
- Azelaic Acid Suspension 10%
- 100% Plant-Derived Squalane
- Non-comedogenic moisturizer
- Sunscreen
Evening Rotation: Evening A (3-4 times weekly):
- Gentle cleanser
- Granactive Retinoid 2% Emulsion
- 100% Plant-Derived Squalane
- Non-comedogenic moisturizer
Evening B (3-4 times weekly):
- Gentle cleanser
- Glycolic Acid 7% Toning Solution
- Niacinamide 10% + Zinc 1%
- 100% Plant-Derived Squalane
- Non-comedogenic moisturizer
Weekly Treatment: AHA 30% + BHA 2% Peeling Solution (on a night when not using other actives)
Expert Tips for Maximizing Results
Dermatologists emphasize these key principles when using The Ordinary products for acne:
1. Introduce Products Gradually
Dr. Taylor recommends: « Add one new product every 2-3 weeks, using it 2-3 times weekly before increasing frequency. This allows you to identify both effective products and potential irritants. »
2. Focus on Consistency Over Quantity
Dr. Chen advises: « Using fewer products consistently is more effective than using many products intermittently. Master a simple routine before adding complexity. »
3. Adjust Based on Seasonal Changes
Dr. Gonzalez notes: « Many acne patients need different routines for different seasons. What works in humid summer months may be too drying in winter. »
4. Document Your Progress
Dr. Johnson suggests: « Take weekly photos in the same lighting to objectively track improvements. Acne changes can be gradual and difficult to notice day-to-day. »
5. Don’t Neglect Hydration
Dr. Park emphasizes: « Even oily, acne-prone skin needs proper hydration. Skipping moisturizer can trigger increased oil production and worsen acne. »
6. Be Patient with Results
Dr. Thompson cautions: « Give any acne regimen at least 8-12 weeks before judging its efficacy. Cell turnover cycles require time to show visible improvements. »
7. Consider Professional Guidance for Severe Cases
Dr. Richards advises: « While over-the-counter products can be remarkably effective, severe or cystic acne may require prescription options. Don’t delay seeking dermatologist care if OTC products aren’t providing improvement after 3 months. »
When to See a Dermatologist
While The Ordinary products can effectively manage many cases of acne, certain situations warrant professional consultation:
- Acne that causes physical pain or discomfort
- Deep, cystic lesions that may lead to scarring
- Acne that persists despite 3 months of consistent over-the-counter treatment
- Sudden onset of severe acne in previously clear skin
- Acne accompanied by other symptoms like excessive facial hair or irregular periods
- Significant psychological distress from acne

Conclusion: Effective, Accessible Acne Care
The Ordinary continues to lead the way in providing science-backed acne solutions that deliver clinical results without clinical prices. By understanding the mechanism of action behind each product and strategically incorporating them into a consistent routine, even stubborn acne can be effectively managed.
Remember that individual results vary, and the key to success lies in patience, consistency, and willingness to adjust your approach based on your skin’s feedback. With these dermatologist-approved products and protocols, clearer skin is an achievable reality—not just a marketing promise.
Whether you’re dealing with occasional breakouts or more persistent acne concerns, The Ordinary’s targeted treatments offer effective solutions for every stage of your skincare journey. By focusing on ingredients with proven efficacy and formulations designed for maximum bioavailability, these products continue to earn dermatologist recommendations and patient praise through 2025.